Survivin

An apoptosis inhibitory protein that contains a single baculoviral IAP repeat (BIR) domain. It associates with MICROTUBULES and functions to regulate cell proliferation as a component of the chromosome passage protein complex (CPC), performing essential roles for localization of the complex, chromosome alignment, segregation during MITOSIS and CYTOKINESIS, and assembly of the MITOTIC SPINDLE. It is expressed by fetal kidney and liver cells and highly expressed in ADENOCARCINOMA and high-grade LYMPHOMA.

Also Known As:

BIRC5 Protein; Baculoviral IAP Repeat-containing Protein 5; Baculoviral IAP Repeat containing Protein 5

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Cell Cycle Proteins: 812
    - Survivin: 5496
  - Cytoskeletal Proteins: 743
    - Microtubule Proteins: 41
      - Microtubule-Associated Proteins: 3319
        Survivin: 5496
  - Intracellular Signaling Peptides and Proteins: 32
    - Apoptosis Regulatory Proteins: 2581
      - Inhibitor of Apoptosis Proteins: 725
        Survivin: 5496
- Peptides: 84029
  - Intracellular Signaling Peptides and Proteins: 32
    - Apoptosis Regulatory Proteins: 2581
      - Inhibitor of Apoptosis Proteins: 725
        Survivin: 5496

L D Barnes Selected Research

L D Barnes Research Topics

Disease

Drug/Important Bio-Agent (IBA)